a 7 hydrochloride — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22538	A-7 hydrochloride		CaMK
	A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.		CaMK
T11638	Ilorasertib hydrochloride	ABT-348 hydrochloride	Aurora Kinase
	Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM). It also suppresses RET tyrosine kinase,...		Aurora Kinase
T20792	W-7 hydrochloride	W 7 HCl,W7 HCl,W-7 HCl	CaMK , Apoptosis , Myosin , PDE
	W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.		CaMK , Apoptosis , Myosin , PDE
T4690	Betrixaban hydrochloride(330942-05-7(free base))	PRT054021 hydrochloride	Factor Xa
	Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).		Factor Xa
T5164	Cabozantinib hydrochloride	XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351	VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
	Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).		VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
T28531	Facinicline hydrochloride	RG3487	5-HT Receptor , AChR
	Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot...		5-HT Receptor , AChR
T6010	Idarubicin hydrochloride	Idamycin,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,4-Demethoxydaunorubicin hydrochloride,Idarubicin HCl,Zavedos	Topoisomerase , Antibacterial , Autophagy , Antifungal
	Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).		Topoisomerase , Antibacterial , Autophagy , Antifungal
T10883L	CRA-026440 hydrochloride	CRA-026440 hydrochloride（847460-34-8 Free base）	HDAC
	CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM...		HDAC
T3050	ML-7 hydrochloride	ML-7 HCl	Serine/threonin kinase , Myosin , YAP , PKA , PKC
	ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-muscle myosin light chain kinase, PKA, and...		Serine/threonin kinase , Myosin , YAP , PKA , PKC
T11719	JMV 2959 hydrochloride (925238-89-7 free base)	JMV 2959 hydrochloride	GHSR
	JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.		GHSR
T1400	Demeclocycline hydrochloride	Declomycin,Clortetrin,Detravis,Demeclocycline HCl	ribosome , Antibacterial , Antibiotic
	Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.		ribosome , Antibacterial , Antibiotic
T4261	BPR1J-097 hydrochloride (1327167-19-0(free base))		FLT
	BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.		FLT
T0486L	Irinotecan Hydrochloride	Camptothecin 11 hydrochloride,CPT-11 hydrochloride	Topoisomerase , Autophagy
	Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptoth...		Topoisomerase , Autophagy
T8402	Regorafenib Hydrochloride	BAY73-4506 hydrochloride	Raf , VEGFR , c-RET , PDGFR , Autophagy
	Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity		Raf , VEGFR , c-RET , PDGFR , Autophagy
T34836	Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride
	Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride is a bioactive chemical.
T34838	Theophylline, 7-(2-oxo-4-piperidinobutyl)-6-thio-, hydrochloride
	Theophylline, 7-(2-oxo-4-piperidinobutyl)-6-thio-, hydrochloride is a bioactive chemical.
T12025	MFZ 10-7 hydrochloride		GluR
	MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM		GluR
T63095	GNE 220 hydrochloride
	GNE 220 (hydrochloride) is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).
T61724	SB 258741 hydrochloride
	SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].
T63622	RF9 hydrochloride
	RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).